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The Pei 2024 meta-analysis has a larger total patient pool (1,458 vs 472), giving it more overall statistical power

Insomnia affects a significant percentage of users, which is why morning dosing is standard

Ipamorelin's defining research characteristic is its selectivity

To overcome challenges such as biosafety, off-target effects, and clinical translatability, strategies successfully explored in other diseases, such as biodegradable or organicinorganic hybrid nanozymes, pH-responsive targeting designs, erythrocyte membrane coatings, and ROS-responsive carriers, may be adapted to enhance tissue specificity and safety in IMID treatment